Cortisol and ACTH responses to severe asphyxia in preterm fetal sheep
نویسندگان
چکیده
منابع مشابه
Male disadvantage? Fetal sex and cardiovascular responses to asphyxia in preterm fetal sheep.
Clinically and experimentally male fetuses are at significantly greater risk of dying or suffering injury at birth, particularly after premature delivery. We undertook a retrospective cohort analysis of 60 female and 65 male singleton preterm fetal sheep (103-104 days, 0.7 gestation) with mean arterial blood pressure (MAP), heart rate, and carotid and femoral blood flow recordings during 25 min...
متن کاملFetal heart rate variability and brain stem injury after asphyxia in preterm fetal sheep.
This study was undertaken to determine the mechanisms mediating changes in fetal heart rate variability (FHRV) during and after exposure to asphyxia in the premature fetus. Preterm fetal sheep at 0.6 of gestation (91 +/- 1 days, term is 147 days) were exposed to either sham occlusion (n = 10) or to complete umbilical cord occlusion for either 20 (n = 7) or 30 min (n = 10). Cord occlusion led to...
متن کاملPolyuria and Impaired Renal Blood Flow after Asphyxia in Preterm Fetal Sheep
Renal impairment is common in preterm infants, often after exposure to hypoxia / asphyxia or other circulatory disturbances. We examined the hypothesis that this association is mediated by reduced renal blood flow (RBF), using a model of asphyxia induced by complete umbilical cord occlusion for 25 min (n=13) or sham occlusion (n=6) in chronically instrumented preterm fetal sheep (104 days, term...
متن کاملNonadditive neuroprotection with early glutamate receptor blockade and delayed hypothermia after asphyxia in preterm fetal sheep.
BACKGROUND AND PURPOSE Hypothermia induced after perinatal hypoxia-ischemia is partially protective. This study examined whether early treatment with the noncompetitive N-methyl-d-aspartate receptor antagonist, dizocilpine, can augment neuroprotection with delayed hypothermia after severe asphyxia in preterm fetal sheep at 0.7 weeks gestation (equivalent to 28-32 weeks in humans). METHODS Fif...
متن کاملNonimmune hydrops fetalis and activation of the renin-angiotensin system after asphyxia in preterm fetal sheep.
This study examined the hypothesis that the development of hydrops fetalis after asphyxia in the 0.6 gestation sheep fetus would be associated with activation of the fetal renin-angiotensin system (RAS). Fetuses were randomly assigned to either sham occlusion (n = 7) or to 30 min of asphyxia induced by complete umbilical cord occlusion for 30 min (n = 8). Asphyxia led to severe bradycardia and ...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 2005
ISSN: 0958-0670
DOI: 10.1113/expphysiol.2005.030320